Best Clinic UK - Aesthetics Awards 2024
& Aesthetic Medicine Awards 2024
Treatments
Polynucleotides are an injectable skin booster treatment which increase collagen and elastin production, resulting in smoother, firmer, more hydrated skin.
Get in touch Request PriceWe have invited only the very best consultants to practice at our specialist clinic.
Our state-of the-art award winning facilities are located right in the heart of London.
Best Clinic Aesthetics Awards 2024
We were awarded Best Clinic London at the industry-leading 2024 Aesthetics Awards.
CQC ‘Outstanding’ Leadership
Our Leadership is rated ‘Outstanding’ by the independent healthcare regulator in England.
20 Years of Medical Distinction
We’re now entering our third decade at the top of our field, with over 100 of the country’s best consultants under our roof.
96% Customer Excellence Rating
We support 30,000 patient appointments each year, 96% of which were rated 5*.
Medically Reviewed 3rd March 2025, by Dr. Susan Mayou (GMC: 2405092) - founder of the Cadogan Clinic and one of the world's leading dermatologists
Polynucleotides are an injectable skin booster treatment which increase collagen and elastin production, resulting in smoother, firmer, more hydrated skin. Also known as a bio-stimulator, Polynucleotides are made up of physically flexible molecules that mirror human DNA's structure.
When injected, Polynucleotides are able to interact with the Fibroblast cells which produce collagen and maintain the structural integrity of the skin. This stimulates the natural production of collagen and elastin. Polynucleotide injections can also improve tissue regeneration, skin tone, and elasticity.
Polynucleotides can be used effectively in delicate areas such as under the eyes and around the neck, as well as being an alternative to treatments such as Dermal Lip Filler.
Get in touchPolynucleotide costs may vary depending on the exact treatment carried out by your consultant.
Get in touchIncluded in Polynucleotide Treatments:
All Polynucleotides treatments are carried out by a consultant plastic surgeon or dermatologist
Custom Polynucleotide treatment to improve the tone and quality of the skin with a natural finish
Polynucleotides London treatment is performed within our state of the art award winning clinic in the heart of Chelsea, London.
Polynucleotides involve minimal downtime
Words from our clients:
“I have used Dr Mayou for years as my children’s dermatologist and was very pleased to discover she could take care of me as well. She has been extremely helpful, checking for melanoma and other skin issues as well as more cosmetic concerns. I have found her to be sensible and practical with a lovely manner and trust she is looking after the whole picture of my skins health and looks.”Jess K
"Everything was brilliant staff were incredibly friendly exact amount of info was given. Have already recommended this company to friends and family."Clare Brooks
“Wonderful service, knowledgeable staff, friendly service and comfortable ambience - well run. I will use you again in the future.“Sarah Tylor
"There is nothing that I feel could be improved at Cadogan Clinic. I was treated and looked after very well the place was very clean. Perfect. Thank you."Emma Grant
"The treatment was for my daughter and the aesthetic practitioner couldn't have been more helpful and informative all through the course of treatment, it was a great treatment with a brilliant outcome. The whole experience was very professional and any worries we went in with were soon taken away after the team greeted us and treated us."Jessica Yates
Polynucleotide skin boosters are an innovative approach to skin rejuvenation and improving skin health.
Polynucleotide benefits include:
We have invited a selection of the country's very best consultants to join us at the Cadogan Clinic so that you can be sure that whatever the nature of your treatment, you will be seeing one of the top practitioners in the country.
Polynucleotide treatment is initially carried out over 2-3 sessions, depending on your concerns. These appointments are usually spaced 2 weeks apart.
You will attend an in-person consultation at Cadogan Clinic to start your treatment plan. During this consultation, you will discuss your concerns and the most effective treatment options for you. If you are happy to proceed, your Polynucleotide treatment can start straight away.
Your consultant will discuss any potential risks and complications with you during your consultation. It is normal to experience some swelling and bruising in the areas that have been treated with Polynucleotides and this usually subsides within 10 days.
Most people start to notice results following their second Polynucleotides treatment. Appointments are needed roughly every 6 months to maintain optimum results.
Polynucleotides are a highly versatile injectable treatment, which can be used to address a number of conditions and concerns affecting many areas.
Fine Lines and Wrinkles
Fine Lines and Wrinkles occur across the face including around the eyes (known as Crow’s Feet) and around the nose and mouth – Marionette Lines, Nasolabial Folds and Smoker’s Lines.
These lines usually appear with age, resulting from a natural breakdown of collagen and elastin in the skin. Polynucleotides naturally stimulate the body’s production of these vital proteins to smooth the appearance of lines and wrinkles.
Dull Skin
Dull Skin is a skin condition which can occur in anyone, regardless of age – however, it becomes more common as people get older, and is often seen in women who are going through menopause. Skin usually looks dull due to a lack of hydration in the skin, which maintains a smooth and bright complexion. Having a dull skin tone can also exacerbate other concerns such as fine lines and wrinkles or textured skin.
Polynucleotides work with Hyaluronic Acid, already found in the skin to increase hydration levels which improves the tone of the skin, resulting in a smooth and youthful appearance.
Dark Under-Eye Circles
Dark Under-Eye Circles can occur for many reasons, and it is important to establish and understand the root cause of this concern to create the most effective treatment plan.
Tear Trough Filler isn’t a viable solution for everyone who is affected by Under-Eye Dark Circles and Polynucleotides eyes treatment can be an effective alternative. By stimulating collagen and elastin production, as well as strengthening the skin in this delicate area, Polynucleotides can smoothen and fill this area leaving a more youthful and open eye area.
Neck Concerns
Polynucleotides are an effective alternative to Dermal Filler and Anti-Ageing Injections for effectively treating common neck concerns such as lines and wrinkles (sometimes known as necklace lines).
The skin around the neck is thinner and more delicate than other areas of the body, so requires appropriate treatment. For individuals, looking for a non-surgical solution to their neck concerns, Polynucleotides are often recommended by surgeons and dermatologists.
Rosacea
Rosacea can be a debilitating skin condition and can be challenging to treat and manage. Although the exact causes of Rosacea are not understood, we do know that inflammation leads to the blood vessels in the skin widening, leading to a red and swollen appearance to the skin.
For some people, polynucleotides may be an effective treatment, as they can help reduce inflammation and hydrate the skin, tackling the uncomfortable dryness often associated with Rosacea. It is important to speak with your Dermatologist to ensure A Polynucleotide injection are an appropriate treatment for you, as Rosacea is a medical condition.
Hand Concerns
Hands are an area which can show signs of ageing prematurely to other areas of the body. This is because the hands are often exposed to the sun and may not be as well protected as the face.
Polynucleotides can be used to treat skin concerns such as pigmentation and age spots and improve the sunken appearance that can occur across the hands with age – as fat naturally breaks down. By treating inflammation and stimulating the production of collagen and elastin the hands will look smoother, with a more even skin tone and more youthful appearance.
What is Polynucleotide treatment?
Polynucleotides treatments are an injectable skin booster treatment which stimulates collagen and elastin production, improving the tone, quality and texture of the skin. They are suited to patients who are concerned about the early signs of ageing and who wish to achieve natural looking results.
What is a Polynucleotide?
A polynucleotide is a chain of nucleotides, the building blocks which makes up DNA chains (two polynucleotides make up one unit of DNA). DNA is the molecule which carries genetic information within the cells, for the development and functioning of any living organism. Due to their bioavailable nature, in a Polynucleotides injection, they are able to interact with Fibroblast cells, which produce collagen and elastin, improving skin tone, texture, and elasticity.
How do Polynucleotides work?
Polynucleotides are fragmented DNA molecules, extracted from salmon. They work by interacting with our Fibroblast cells, which produce collagen and elastin, which are both structurally integral to the skin. Collagen and elastin production slows as we age, which can lead to signs of ageing such as fine lines and wrinkles or dull skin. Polynucelotide injection treatment encourage the production of collagen and elastin, firming and strengthening the skin, and targeting common signs of ageing.
How many sessions of Polynucleotides do you need?
Depending on your concerns, Polynucleotide treatment typically involves 2-3 inital treatments, spaced 2 weeks apart. After these initial Polyncucleotide skin booster treatments, most patients find they need maintenance appointments every 6 months to maintain their results.
The Patient Journey. What you can expect on your journey with us
You will meet with one of our highly trained cosmetic dermatologists or surgeons at the Clinic on Sloane Street, Chelsea, for a no-obligation in-person assessment.
Get in touchThe Cadogan Clinic is based at 120 Sloane Street in Chelsea, just off Sloane Square and the Kings Road.
We are accessible by all major bus routes that pass through Sloane Square and Sloane Street, as well as Sloane Square tube station.
We are just a 5 minute walk northwards up Sloane Street once you have arrived at Sloane Square.
Local pay parking is available just around the corner from the Clinic on Cadogan Gate, Cadogan Square and Cadogan Gardens. Our local residential parking zone is the Royal Borough of Kensington & Chelsea.
Address: 120 Sloane Street, Chelsea, London, SW1X 9BW
Treatments
We believe in the delivery of excellent outcomes and results, and exceptional levels of service. Our outcomes are natural and long-lasting, and we remain the premier choice for cosmetic surgery treatments in the UK.
Treatments
Anti-Wrinkle Injections
Treatments
Cheek Fillers
Treatments
Dermal Fillers
Treatments
Lip Fillers
Treatments
Non-Surgical Rhinoplasty
Treatments
Profhilo
Treatments
Tear Trough Filler
Treatments
8 Point Facelift
Treatments
Dissolving Filler
Treatments
Hand Rejuvenation
2024
Aesthetic Medicine 2024
UK Clinic of the Year
2024
Aesthetic Awards
Best Clinic, London
2024
Aesthetic Medicine
Best Clinic, London
2023
Aesthetic Awards
Highly Commended
2021
Aesthetic Awards
Highly Commended
2021
MyFaceMyBody
Best Plastic Surgery Clinic, UK
2020
MyFaceMyBody Awards
Best Plastic Surgery Clinic, UK
2019
MyFaceMyBody Awards
Best Plastic Surgery Clinic, UK